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Osmotic and hypoxic induction of the complement factor C9 in cultured human retinal pigment epithelial cells: Regulation of VEGF and NLRP3 expression

PURPOSE: Variants of complement factor genes, hypoxia and oxidative stress of the outer retina, and systemic hypertension affect the risk of age-related macular degeneration. Hypertension often results from the high intake of dietary salt that increases extracellular osmolarity. We determined the ef...

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Detalles Bibliográficos
Autores principales:	Hollborn, Margrit, Ackmann, Charlotte, Kuhrt, Heidrun, Doktor, Fabian, Kohen, Leon, Wiedemann, Peter, Bringmann, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066273/ https://www.ncbi.nlm.nih.gov/pubmed/30090015

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