Development and Initial Characterization of a Novel Ghrelin Receptor CRISPR/Cas9 Knockout Wistar Rat Model

BACKGROUND/OBJECTIVES: Ghrelin, a stomach-derived hormone implicated in numerous behaviors including feeding, reward, stress, and addictive behaviors, acts through binding to the growth hormone secretagogue receptor (GHSR). Here, we present the development, verification and initial characterization...

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Detalles Bibliográficos
Autores principales: Zallar, L.J., Tunstall, B.J., Richie, C.T., Zhang, Y.J., You, Z.B., Gardner, E.L., Heilig, M., Pickel, J., Koob, G.F., Vendruscolo, L.F., Harvey, B.K., Leggio, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066458/
https://www.ncbi.nlm.nih.gov/pubmed/29453460
http://dx.doi.org/10.1038/s41366-018-0013-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066458/
https://www.ncbi.nlm.nih.gov/pubmed/29453460
http://dx.doi.org/10.1038/s41366-018-0013-5

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