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Structural visualization of RNA polymerase III transcription machineries

RNA polymerase III (Pol III) transcription initiation requires the action of the transcription factor IIIB (TFIIIB) and is highly regulated. Here, we determine the structures of Pol III pre-initiation complexes (PICs) using single particle cryo-electron microscopy (cryo-EM). We observe stable Pol II...

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Detalles Bibliográficos
Autores principales:	Han, Yan, Yan, Chunli, Fishbain, Susan, Ivanov, Ivaylo, He, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066478/ https://www.ncbi.nlm.nih.gov/pubmed/30083386 http://dx.doi.org/10.1038/s41421-018-0044-z

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