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Phase 1/2 trial of ixazomib, cyclophosphamide and dexamethasone in patients with previously untreated symptomatic multiple myeloma
Ixazomib is the first oral proteasome inhibitor to enter the clinic. Given the efficacy of bortezomib in combination with cyclophosphamide and dexamethasone, we studied the combination of ixazomib, cyclophosphamide and dexamethasone (ICd) in newly diagnosed multiple myeloma (NDMM) and patients with...
Autores principales: | Kumar, Shaji K., Buadi, Francis K., LaPlant, Betsy, Halvorson, Alese, Leung, Nelson, Kapoor, Prashant, Dingli, David, Gertz, Morie A., Go, Ronald S., Bergsagel, P. Leif, Lin, Yi, Dispenzieri, Angela, Hwa, Yi Lisa, Fonder, Amie, Hobbs, Miriam, Fonseca, Rafael, Hayman, Suzanne R., Stewart, A. Keith, Lust, John A., Mikhael, Joseph, Gonsalves, Wilson, Reeder, Craig, Skacel, Tomas, Rajkumar, S. Vincent, Lacy, Martha Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066484/ https://www.ncbi.nlm.nih.gov/pubmed/30061664 http://dx.doi.org/10.1038/s41408-018-0106-3 |
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