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Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?

Drug resistance is a major cause for therapeutic failure in non-small cell lung cancer (NSCLC) leading to tumor recurrence and disease progression. Cell intrinsic mechanisms of resistance include changes in the expression of drug transporters, activation of pro-survival, and anti-apoptotic pathways,...

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Detalles Bibliográficos
Autores principales:	Sosa Iglesias, Venus, Giuranno, Lorena, Dubois, Ludwig J., Theys, Jan, Vooijs, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066509/ https://www.ncbi.nlm.nih.gov/pubmed/30087852 http://dx.doi.org/10.3389/fonc.2018.00267

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