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ErbB4 Preserves Blood-Brain Barrier Integrity via the YAP/PIK3CB Pathway After Subarachnoid Hemorrhage in Rats
Studies have suggested that blood-brain barrier (BBB) disruption contributes to the pathogenesis of early brain injury after subarachnoid haemorrhage (SAH). Activation of the receptor tyrosine kinase ErbB4 can cause intramembrane proteolysis and release a soluble intracellular domain (ICD) that modu...
Autores principales: | Qian, Huan, Dou, Zhangqi, Ruan, Wu, He, Pingyou, Zhang, John H., Yan, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066511/ https://www.ncbi.nlm.nih.gov/pubmed/30087588 http://dx.doi.org/10.3389/fnins.2018.00492 |
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