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Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress

Revascularization therapies have been established as the treatment mainstay for acute ischemic stroke. However, a substantial number of patients are either ineligible for revascularization therapy, or the treatment fails or is futile. At present, non-contrast computed tomography is the first-line ne...

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Autores principales: Bang, Oh Young, Chung, Jong-Won, Son, Jeong Pyo, Ryu, Wi-Sun, Kim, Dong-Eog, Seo, Woo-Keun, Kim, Gyeong-Moon, Kim, Yoon-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066534/
https://www.ncbi.nlm.nih.gov/pubmed/30087652
http://dx.doi.org/10.3389/fneur.2018.00586
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author Bang, Oh Young
Chung, Jong-Won
Son, Jeong Pyo
Ryu, Wi-Sun
Kim, Dong-Eog
Seo, Woo-Keun
Kim, Gyeong-Moon
Kim, Yoon-Chul
author_facet Bang, Oh Young
Chung, Jong-Won
Son, Jeong Pyo
Ryu, Wi-Sun
Kim, Dong-Eog
Seo, Woo-Keun
Kim, Gyeong-Moon
Kim, Yoon-Chul
author_sort Bang, Oh Young
collection PubMed
description Revascularization therapies have been established as the treatment mainstay for acute ischemic stroke. However, a substantial number of patients are either ineligible for revascularization therapy, or the treatment fails or is futile. At present, non-contrast computed tomography is the first-line neuroimaging modality for patients with acute stroke. The use of magnetic resonance imaging (MRI) to predict the response to early revascularization therapy and to identify patients for delayed treatment is desirable. MRI could provide information on stroke pathophysiologies, including the ischemic core, perfusion, collaterals, clot, and blood–brain barrier status. During the past 20 years, there have been significant advances in neuroimaging as well as in revascularization strategies for treating patients with acute ischemic stroke. In this review, we discuss the role of MRI and post-processing, including machine-learning techniques, and recent advances in MRI-based triage for revascularization therapies in acute ischemic stroke.
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spelling pubmed-60665342018-08-07 Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress Bang, Oh Young Chung, Jong-Won Son, Jeong Pyo Ryu, Wi-Sun Kim, Dong-Eog Seo, Woo-Keun Kim, Gyeong-Moon Kim, Yoon-Chul Front Neurol Neurology Revascularization therapies have been established as the treatment mainstay for acute ischemic stroke. However, a substantial number of patients are either ineligible for revascularization therapy, or the treatment fails or is futile. At present, non-contrast computed tomography is the first-line neuroimaging modality for patients with acute stroke. The use of magnetic resonance imaging (MRI) to predict the response to early revascularization therapy and to identify patients for delayed treatment is desirable. MRI could provide information on stroke pathophysiologies, including the ischemic core, perfusion, collaterals, clot, and blood–brain barrier status. During the past 20 years, there have been significant advances in neuroimaging as well as in revascularization strategies for treating patients with acute ischemic stroke. In this review, we discuss the role of MRI and post-processing, including machine-learning techniques, and recent advances in MRI-based triage for revascularization therapies in acute ischemic stroke. Frontiers Media S.A. 2018-07-24 /pmc/articles/PMC6066534/ /pubmed/30087652 http://dx.doi.org/10.3389/fneur.2018.00586 Text en Copyright © 2018 Bang, Chung, Son, Ryu, Kim, Seo, Kim and Kim. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Bang, Oh Young
Chung, Jong-Won
Son, Jeong Pyo
Ryu, Wi-Sun
Kim, Dong-Eog
Seo, Woo-Keun
Kim, Gyeong-Moon
Kim, Yoon-Chul
Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress
title Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress
title_full Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress
title_fullStr Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress
title_full_unstemmed Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress
title_short Multimodal MRI-Based Triage for Acute Stroke Therapy: Challenges and Progress
title_sort multimodal mri-based triage for acute stroke therapy: challenges and progress
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066534/
https://www.ncbi.nlm.nih.gov/pubmed/30087652
http://dx.doi.org/10.3389/fneur.2018.00586
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