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Mycobacterium Growth Inhibition Assay of Human Alveolar Macrophages as a Correlate of Immune Protection Following Mycobacterium bovis Bacille Calmette–Guérin Vaccination
BACKGROUND: In order to eliminate tuberculosis (TB), an effective vaccine is urgently needed to prevent infection with Mycobacterium tuberculosis. A key obstacle for the development of novel TB vaccines is the lack of surrogate markers for immune protection against M. tuberculosis. METHODS: We inves...
Autores principales: | Radloff, Juliane, Heyckendorf, Jan, van der Merwe, Lize, Sanchez Carballo, Patricia, Reiling, Norbert, Richter, Elvira, Lange, Christoph, Kalsdorf, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066571/ https://www.ncbi.nlm.nih.gov/pubmed/30087678 http://dx.doi.org/10.3389/fimmu.2018.01708 |
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