Cargando…

Therapeutic Effect of Repurposed Temsirolimus in Lung Adenocarcinoma Model

Lung cancer is one of the major cause of cancer-related deaths worldwide. The poor prognosis and resistance to both radiation and chemotherapy urged the development of potential targets for lung cancer treatment. In this study, using a network-based cellular signature bioinformatics approach, we rep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Hsuen-Wen, Wu, Min-Ju, Lin, Zih-Miao, Wang, Chueh-Yi, Cheng, Shu-Yun, Lin, Yen-Kuang, Chow, Yen-Hung, Ch’ang, Hui-Ju, Chang, Vincent H. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066584/ https://www.ncbi.nlm.nih.gov/pubmed/30087612 http://dx.doi.org/10.3389/fphar.2018.00778

Ejemplares similares

Characterization of a transgenic mouse model exhibiting spontaneous lung adenocarcinomas with a metastatic phenotype
por: Chang, Hsuen-Wen, et al.
Publicado: (2017)

Evidence for Bell-Shaped Dose-Response Emetic Effects of Temsirolimus and Analogs: The Broad-Spectrum Antiemetic Efficacy of a Large Dose of Temsirolimus Against Diverse Emetogens in the Least Shrew (Cryptotis parva)
por: Belkacemi, Louiza, et al.
Publicado: (2022)

Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus
por: Boni, J P, et al.
Publicado: (2008)

Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency
por: Tsai, Yi-Chih, et al.
Publicado: (2021)

Association Between Cholangiocarcinoma and Proton Pump Inhibitors Use: A Nested Case-Control Study
por: Peng, Yen-Chun, et al.
Publicado: (2018)

A Review of Treatment of Coronavirus Disease 2019 (COVID-19): Therapeutic Repurposing and Unmet Clinical Needs
por: Chen, Po-Lin, et al.
Publicado: (2020)

Selection of patients with pancreatic adenocarcinoma who may benefit from radiotherapy
por: Jan, I-Shiow, et al.
Publicado: (2023)

Hydralazine Associated With Reduced Therapeutic Phlebotomy Frequency in a Nationwide Cohort Study: Real-World Effectiveness for Drug Repurposing
por: Lin, Wei-Zhi, et al.
Publicado: (2022)

Temsirolimus Enhances Anti-Cancer Immunity by Inducing Autophagy-Mediated Degradation of the Secretion of Small Extracellular Vesicle PD-L1
por: Park, Seong-Sik, et al.
Publicado: (2022)

Repurposing Drugs, Ongoing Vaccine, and New Therapeutic Development Initiatives Against COVID-19
por: Saha, Rudra P., et al.
Publicado: (2020)

Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics
por: Charrez, Bérénice, et al.
Publicado: (2021)

Therapeutic Effectiveness and Safety of Repurposing Drugs for the Treatment of COVID-19: Position Standing in 2021
por: Alam, Safaet, et al.
Publicado: (2021)

Evaluating the activity of temsirolimus in neuroendocrine cancer
por: O'Donnell, P H, et al.
Publicado: (2007)

Editorial: Cancer neuroscience: Drug repurposing targeting the innervated niche
por: Jin, Ming-Zhu, et al.
Publicado: (2023)

Effectiveness of Deferred Combined Androgen Blockade Therapy Predicts Efficacy in Abiraterone Acetate Treated Metastatic Castration-Resistant Prostate Cancer Patients after Docetaxel
por: Li, Jian-Ri, et al.
Publicado: (2017)

Repurposing of Bromocriptine for Cancer Therapy
por: Seo, Ean-Jeong, et al.
Publicado: (2018)

Geriatric Nutritional Risk Index as a Prognostic Marker for Patients With Metastatic Castration-Resistant Prostate Cancer Receiving Docetaxel
por: Chang, Li-Wen, et al.
Publicado: (2021)

In-silico studies to recognize repurposing therapeutics toward arginase-I inhibitors as a potential onco-immunomodulators
por: Zaki, Magdi E. A., et al.
Publicado: (2023)

Reply: Evaluating the activity of temsirolimus in neuroendocrine cancer
por: Duran, I, et al.
Publicado: (2007)

Addition of Bevacizumab to Temsirolimus in Kidney Cancer Patients
por: Boyle, H., et al.
Publicado: (2011)

A pilot study of temsirolimus and body composition
por: Veasey-Rodrigues, Heloisa, et al.
Publicado: (2013)

Repurposing phosphodiesterase-5 inhibitors as chemoadjuvants
por: Tiwari, Amit K., et al.
Publicado: (2013)

Repurposing of Antibiotics: Sense or Non-sense
por: Talat, Absar, et al.
Publicado: (2022)

Repurposing Tranexamic Acid as an Anticancer Agent
por: Law, Mary E., et al.
Publicado: (2022)

Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis
por: Gan, Donghao, et al.
Publicado: (2021)

Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs
por: Lee, Chiming, et al.
Publicado: (2019)

Trajectories of mobility difficulty and falls in community-dwelling adults aged 50 + in Taiwan from 2003 to 2015
por: Kuo, Fang-Lin, et al.
Publicado: (2022)

Sciatic Nerve Intrafascicular Injection Induces Neuropathy by Activating the Matrix Modulators MMP-9 and TIMP-1
por: Tseng, Kuang-Yi, et al.
Publicado: (2022)

The Role of Consolidation Chemoradiotherapy in Locally Advanced Pancreatic Cancer Receiving Chemotherapy: An Updated Systematic Review and Meta-Analysis
por: Chang, Jeffrey S., et al.
Publicado: (2018)

Human SCARB2 Transgenic Mice as an Infectious Animal Model for Enterovirus 71
por: Lin, Yi-Wen, et al.
Publicado: (2013)

FBXW7 and human tumors: mechanisms of drug resistance and potential therapeutic strategies
por: Wang, Wanqing, et al.
Publicado: (2023)

Therapeutic effects of herbal-medicine combined therapy for COVID-19: A systematic review and meta-analysis of randomized controlled trials
por: Chien, Tsai-Ju, et al.
Publicado: (2022)

Editorial: Drug Repurposing for COVID-19 Therapy
por: Maldonado, Rafael, et al.
Publicado: (2021)

Disulfiram in glioma: Literature review of drug repurposing
por: Zhong, Shiyu, et al.
Publicado: (2022)

Screening of GPCR drugs for repurposing in breast cancer
por: Abdulkareem, Noor Mazin, et al.
Publicado: (2022)

Heat Shock protein 90: Role in Enterovirus 71 Entry and Assembly and Potential Target for Therapy
por: Tsou, Yueh-Liang, et al.
Publicado: (2013)

Cilostazol Ameliorates Peripheral Neuropathic Pain in Streptozotocin-Induced Type I Diabetic Rats
por: Cheng, Kuang-I., et al.
Publicado: (2022)

Therapeutic Targeting of Autophagy in Pancreatic Ductal Adenocarcinoma
por: Raufi, Alexander G., et al.
Publicado: (2021)

Nicardipine Inhibits Breast Cancer Migration via Nrf2/HO-1 Axis and Matrix Metalloproteinase-9 Regulation
por: Chen, Yen-Chang, et al.
Publicado: (2021)

Temsirolimus in the treatment of relapsed or refractory mantle cell lymphoma
por: Samad, Nousheen, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tl68l12kta1sqedrp6mb9b5uba