A tRNA-derived small RNA regulates ribosome biogenesis

tRNA-derived small RNAs (tsRNAs; also called tRNA-derived fragments (tRFs)) are an abundant class of small non-coding RNAs whose biological roles are not well defined. We show that inhibition of a specific tsRNA, LeuCAG3′tsRNA, induces apoptosis in rapidly dividing cells in vitro and in a patient-de...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hak Kyun, Fuchs, Gabriele, Wang, Shengchun, Wei, Wei, Zhang, Yue, Park, Hyesuk, Roy-Chaudhuri, Biswajoy, Li, Pan, Xu, Jianpeng, Chu, Kirk, Zhang, Feijie, Chua, Mei-Sze, So, Samuel, Zhang, Qiangfeng Cliff, Sarnow, Peter, Kay, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066594/
https://www.ncbi.nlm.nih.gov/pubmed/29186115
http://dx.doi.org/10.1038/nature25005

Ejemplares similares

Ejemplares similares