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Dynamic Modeling of Streptococcus pneumoniae Competence Provides Regulatory Mechanistic Insights Into Its Tight Temporal Regulation

In the human pathogen Streptococcus pneumoniae, the gene regulatory circuit leading to the transient state of competence for natural transformation is based on production of an auto-inducer that activates a positive feedback loop. About 100 genes are activated in two successive waves linked by a cen...

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Detalles Bibliográficos
Autores principales:	Weyder, Mathias, Prudhomme, Marc, Bergé, Mathieu, Polard, Patrice, Fichant, Gwennaele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066662/ https://www.ncbi.nlm.nih.gov/pubmed/30087661 http://dx.doi.org/10.3389/fmicb.2018.01637

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