Cargando…
The involvement of tau in nucleolar transcription and the stress response
Tau is known for its pathological role in neurodegenerative diseases, including Alzheimer’s disease (AD) and other tauopathies. Tau is found in many subcellular compartments such as the cytosol and the nucleus. Although its normal role in microtubule binding is well established, its nuclear role is...
Autores principales: | Maina, Mahmoud B., Bailey, Laura J., Wagih, Sherin, Biasetti, Luca, Pollack, Saskia J., Quinn, James P., Thorpe, Julian R., Doherty, Aidan J., Serpell, Louise C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066928/ https://www.ncbi.nlm.nih.gov/pubmed/30064522 http://dx.doi.org/10.1186/s40478-018-0565-6 |
Ejemplares similares
-
The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction
por: Maina, Mahmoud B., et al.
Publicado: (2018) -
The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease
por: Al-Hilaly, Youssra K., et al.
Publicado: (2016) -
Paired Helical Filament-Forming Region of Tau (297–391) Influences Endogenous Tau Protein and Accumulates in Acidic Compartments in Human Neuronal Cells
por: Pollack, Saskia J., et al.
Publicado: (2020) -
Nuclear Tau and Its Potential Role in Alzheimer’s Disease
por: Bukar Maina, Mahmoud, et al.
Publicado: (2016) -
Tau (297‐391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer’s disease brain
por: Al‐Hilaly, Youssra K., et al.
Publicado: (2019)