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miR-106a Reduces 5-Fluorouracil (5-FU) Sensitivity of Colorectal Cancer by Targeting Dual-Specificity Phosphatases 2 (DUSP2)

BACKGROUND: 5-Fluorouracil (5-FU)-based chemotherapy is a conventional therapeutic approach for the treatment of patients with colorectal cancer (CRC). However, development of 5-FU resistance frequently occurs. We explored a potential method for regulating the sensitivity to 5-FU-based chemotherapy...

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Detalles Bibliográficos
Autores principales: Qin, Yan, Chen, Xiao, Liu, Zhihu, Tian, Xiaopeng, Huo, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067019/
https://www.ncbi.nlm.nih.gov/pubmed/30011263
http://dx.doi.org/10.12659/MSM.910016

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