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TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells

Transforming growth factor β1 (TGF-β1) plays a role in the maintenance of quiescent hematopoietic stem cells (HSCs) in vivo. We asked whether TGF-β1 controls the cell cycle status of HSCs in vitro to enhance the reconstitution activity. To examine the effect of TGF-β1 on the HSC function, we used an...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaofang, Dong, Fang, Zhang, Sen, Yang, Wanzhu, Yu, Wenying, Wang, Zhao, Zhang, Shanshan, Wang, Jinhong, Ma, Shihui, Wu, Peng, Gao, Yun, Dong, Ji, Tang, Fuchou, Cheng, Tao, Ema, Hideo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067088/ https://www.ncbi.nlm.nih.gov/pubmed/29937145 http://dx.doi.org/10.1016/j.stemcr.2018.05.017

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