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Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells

The molecular mechanism underpinning the specification of the ectoderm, a transient germ-layer tissue, during mouse gastrulation was examined here in a stem cell-based model. We captured a self-renewing cell population with enhanced ectoderm potency from mouse epiblast stem cells (EpiSCs) by suppres...

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Detalles Bibliográficos
Autores principales:	Liu, Chang, Wang, Ran, He, Zhisong, Osteil, Pierre, Wilkie, Emilie, Yang, Xianfa, Chen, Jun, Cui, Guizhong, Guo, Wenke, Chen, Yingying, Peng, Guangdun, Tam, Patrick P.L., Jing, Naihe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067151/ https://www.ncbi.nlm.nih.gov/pubmed/30008328 http://dx.doi.org/10.1016/j.stemcr.2018.05.019

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