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Long term adaptation of a microbial population to a permanent metabolic constraint: overcoming thymineless death by experimental evolution of Escherichia coli

BACKGROUND: To maintain populations of microbial cells under controlled conditions of growth and environment for an indefinite duration is a prerequisite for experimentally evolving natural isolates of wild-type species or recombinant strains. This goal is beyond the scope of current continuous cult...

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Detalles Bibliográficos
Autores principales:	de Crécy-Lagard, Valérie A, Bellalou, Jacques, Mutzel, Rupert, Marlière, Philippe
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2001
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60676/ https://www.ncbi.nlm.nih.gov/pubmed/11737878 http://dx.doi.org/10.1186/1472-6750-1-10

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