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Perturbing the Hypothalamic–Pituitary–Adrenal Axis: A Mathematical Model for Interpreting PTSD Assessment Tests

We use a dynamical systems model of the hypothalamic–pituitary–adrenal (HPA) axis to understand the mechanisms underlying clinical protocols used to probe patient stress response. Specifically, we address dexamethasone (DEX) and ACTH challenge tests, which probe pituitary and adrenal gland responses...

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Detalles Bibliográficos
Autores principales: Kim, Lae Un, D’Orsogna, Maria R., Chou, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MIT Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067831/
https://www.ncbi.nlm.nih.gov/pubmed/30090861
http://dx.doi.org/10.1162/CPSY_a_00013