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Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception

How prior knowledge shapes perceptual processing across the human brain, particularly in the frontoparietal (FPN) and default-mode (DMN) networks, remains unknown. Using ultra-high-field (7T) functional magnetic resonance imaging (fMRI), we elucidated the effects that the acquisition of prior knowle...

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Autores principales: González-García, Carlos, Flounders, Matthew W, Chang, Raymond, Baria, Alexis T, He, Biyu J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067880/
https://www.ncbi.nlm.nih.gov/pubmed/30063006
http://dx.doi.org/10.7554/eLife.36068
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author González-García, Carlos
Flounders, Matthew W
Chang, Raymond
Baria, Alexis T
He, Biyu J
author_facet González-García, Carlos
Flounders, Matthew W
Chang, Raymond
Baria, Alexis T
He, Biyu J
author_sort González-García, Carlos
collection PubMed
description How prior knowledge shapes perceptual processing across the human brain, particularly in the frontoparietal (FPN) and default-mode (DMN) networks, remains unknown. Using ultra-high-field (7T) functional magnetic resonance imaging (fMRI), we elucidated the effects that the acquisition of prior knowledge has on perceptual processing across the brain. We observed that prior knowledge significantly impacted neural representations in the FPN and DMN, rendering responses to individual visual images more distinct from each other, and more similar to the image-specific prior. In addition, neural representations were structured in a hierarchy that remained stable across perceptual conditions, with early visual areas and DMN anchored at the two extremes. Two large-scale cortical gradients occur along this hierarchy: first, dimensionality of the neural representational space increased along the hierarchy; second, prior’s impact on neural representations was greater in higher-order areas. These results reveal extensive and graded influences of prior knowledge on perceptual processing across the brain.
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spelling pubmed-60678802018-08-06 Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception González-García, Carlos Flounders, Matthew W Chang, Raymond Baria, Alexis T He, Biyu J eLife Neuroscience How prior knowledge shapes perceptual processing across the human brain, particularly in the frontoparietal (FPN) and default-mode (DMN) networks, remains unknown. Using ultra-high-field (7T) functional magnetic resonance imaging (fMRI), we elucidated the effects that the acquisition of prior knowledge has on perceptual processing across the brain. We observed that prior knowledge significantly impacted neural representations in the FPN and DMN, rendering responses to individual visual images more distinct from each other, and more similar to the image-specific prior. In addition, neural representations were structured in a hierarchy that remained stable across perceptual conditions, with early visual areas and DMN anchored at the two extremes. Two large-scale cortical gradients occur along this hierarchy: first, dimensionality of the neural representational space increased along the hierarchy; second, prior’s impact on neural representations was greater in higher-order areas. These results reveal extensive and graded influences of prior knowledge on perceptual processing across the brain. eLife Sciences Publications, Ltd 2018-07-31 /pmc/articles/PMC6067880/ /pubmed/30063006 http://dx.doi.org/10.7554/eLife.36068 Text en http://creativecommons.org/publicdomain/zero/1.0/ http://creativecommons.org/publicdomain/zero/1.0/This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication (http://creativecommons.org/publicdomain/zero/1.0/) .
spellingShingle Neuroscience
González-García, Carlos
Flounders, Matthew W
Chang, Raymond
Baria, Alexis T
He, Biyu J
Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception
title Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception
title_full Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception
title_fullStr Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception
title_full_unstemmed Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception
title_short Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception
title_sort content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067880/
https://www.ncbi.nlm.nih.gov/pubmed/30063006
http://dx.doi.org/10.7554/eLife.36068
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