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Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

The hair cell mechanotransduction (MET) channel complex is essential for hearing, yet it’s molecular identity and structure remain elusive. The transmembrane channel–like 1 (TMC1) protein localizes to the site of the MET channel, interacts with the tip-link responsible for mechanical gating, and gen...

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Detalles Bibliográficos
Autores principales:	Ballesteros, Angela, Fenollar-Ferrer, Cristina, Swartz, Kenton Jon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067890/ https://www.ncbi.nlm.nih.gov/pubmed/30063209 http://dx.doi.org/10.7554/eLife.38433

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