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Maternal embryonic leucine zipper kinase inhibitor OTSSP167 has preclinical activity in multiple myeloma bone disease
Multiple myeloma bone disease is characterized by an uncoupling of bone remodeling in the multiple myeloma microenvironment, resulting in the development of lytic bone lesions. Most myeloma patients suffer from these bone lesions, which not only cause morbidity but also negatively impact survival. T...
Autores principales: | Muller, Joséphine, Bolomsky, Arnold, Dubois, Sophie, Duray, Elodie, Stangelberger, Kathrin, Plougonven, Erwan, Lejeune, Margaux, Léonard, Angélique, Marty, Caroline, Hempel, Ute, Baron, Frédéric, Beguin, Yves, Cohen-Solal, Martine, Ludwig, Heinz, Heusschen, Roy, Caers, Jo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068043/ https://www.ncbi.nlm.nih.gov/pubmed/29748441 http://dx.doi.org/10.3324/haematol.2017.185397 |
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