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Improvement of antibody affinity by introduction of basic amino acid residues into the framework region
Antibodies are widely used not only as therapeutic agents but also as research tools and diagnostic agents, and extensive efforts have been made to generate antibodies that have higher affinity. It was recently reported that introduction of charged residues into the framework region of an antibody i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068084/ https://www.ncbi.nlm.nih.gov/pubmed/30073208 http://dx.doi.org/10.1016/j.bbrep.2018.07.005 |