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Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway

Cellular oxidative stress plays a vital role in the pathological process of neural damage in cerebral ischemia/reperfusion (I/R). The breast cancer susceptibility protein 1 (BRCA1), a tumor suppressor, can modulate cellular antioxidant response and DNA repair. Yet the role of BRCA1 in cerebral I/R i...

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Detalles Bibliográficos
Autores principales:	Xu, Pengfei, Liu, Qian, Xie, Yi, Shi, Xiaolei, Li, Yunzi, Peng, Mengna, Guo, Hongquan, Sun, Rui, Li, Juanji, Hong, Ye, Liu, Xinfeng, Xu, Gelin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068089/ https://www.ncbi.nlm.nih.gov/pubmed/30014904 http://dx.doi.org/10.1016/j.redox.2018.06.012

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