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Identification of a 57S translation complex containing closed-loop factors and the 60S ribosome subunit
In eukaryotic translation the 60S ribosome subunit has not been proposed to interact with mRNA or closed-loop factors eIF4E, eIF4G, and PAB1. Using analytical ultracentrifugation with fluorescent detection system, we have identified a 57S translation complex that contains the 60S ribosome, mRNA, and...
Autores principales: | Denis, Clyde L., Laue, Thomas M., Wang, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068138/ https://www.ncbi.nlm.nih.gov/pubmed/30065356 http://dx.doi.org/10.1038/s41598-018-29832-6 |
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