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L-tyrosine supplementation does not ameliorate skeletal muscle dysfunction in zebrafish and mouse models of dominant skeletal muscle α-actin nemaline myopathy

L-tyrosine supplementation may provide benefit to nemaline myopathy (NM) patients, however previous studies are inconclusive, with no elevation of L-tyrosine levels in blood or tissue reported. We evaluated the ability of L-tyrosine treatments to improve skeletal muscle function in all three publish...

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Detalles Bibliográficos
Autores principales: Messineo, Adriana M., Gineste, Charlotte, Sztal, Tamar E., McNamara, Elyshia L., Vilmen, Christophe, Ogier, Augustin C., Hahne, Dorothee, Bendahan, David, Laing, Nigel G., Bryson-Richardson, Robert J., Gondin, Julien, Nowak, Kristen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068151/
https://www.ncbi.nlm.nih.gov/pubmed/30065346
http://dx.doi.org/10.1038/s41598-018-29437-z

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