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GM-CSF driven myeloid cells in adipose tissue link weight gain and insulin resistance via formation of 2-aminoadipate

In a GM-CSF driven myeloid cell deficient mouse model (Csf2(−/−)) that has preserved insulin sensitivity despite increased adiposity, we used unbiased three-dimensional integration of proteome profiles, metabolic profiles, and gene regulatory networks to understand adipose tissue proteome-wide chang...

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Detalles Bibliográficos
Autores principales:	Plubell, Deanna L., Fenton, Alexandra M., Wilmarth, Phillip A., Bergstrom, Paige, Zhao, Yuqi, Minnier, Jessica, Heinecke, Jay W., Yang, Xia, Pamir, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068153/ https://www.ncbi.nlm.nih.gov/pubmed/30065264 http://dx.doi.org/10.1038/s41598-018-29250-8

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