Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis

The importance of neutrophils in the pathology of tuberculosis (TB) has been recently established. We demonstrated that TB lesions in man are hypoxic, but how neutrophils in hypoxia influence lung tissue damage is unknown. We investigated the effect of hypoxia on neutrophil-derived enzymes and tissu...

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Detalles Bibliográficos
Autores principales: Ong, Catherine W. M., Fox, Katharine, Ettorre, Anna, Elkington, Paul T., Friedland, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068197/
https://www.ncbi.nlm.nih.gov/pubmed/30065292
http://dx.doi.org/10.1038/s41598-018-29659-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068197/
https://www.ncbi.nlm.nih.gov/pubmed/30065292
http://dx.doi.org/10.1038/s41598-018-29659-1

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