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Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis
The importance of neutrophils in the pathology of tuberculosis (TB) has been recently established. We demonstrated that TB lesions in man are hypoxic, but how neutrophils in hypoxia influence lung tissue damage is unknown. We investigated the effect of hypoxia on neutrophil-derived enzymes and tissu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068197/ https://www.ncbi.nlm.nih.gov/pubmed/30065292 http://dx.doi.org/10.1038/s41598-018-29659-1 |