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Age Alters Chromatin Structure and Expression of SUMO Proteins under Stress Conditions in Human Adipose-Derived Stem Cells

Adult stem cells play a critical role in tissue homeostasis and repair. Aging leads to a decline in stem cells’ regenerative capacity that contributes significantly to the maintenance of organ and tissue functions. Age-dependent genomic and epigenetic modifications together play a role in the disrup...

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Detalles Bibliográficos
Autores principales: Shan, Xiaoyin, Roberts, Cleresa, Lan, Yemin, Percec, Ivona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068198/
https://www.ncbi.nlm.nih.gov/pubmed/30065345
http://dx.doi.org/10.1038/s41598-018-29775-y