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Age Alters Chromatin Structure and Expression of SUMO Proteins under Stress Conditions in Human Adipose-Derived Stem Cells
Adult stem cells play a critical role in tissue homeostasis and repair. Aging leads to a decline in stem cells’ regenerative capacity that contributes significantly to the maintenance of organ and tissue functions. Age-dependent genomic and epigenetic modifications together play a role in the disrup...
Autores principales: | Shan, Xiaoyin, Roberts, Cleresa, Lan, Yemin, Percec, Ivona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068198/ https://www.ncbi.nlm.nih.gov/pubmed/30065345 http://dx.doi.org/10.1038/s41598-018-29775-y |
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