Immunophenotype and Transcriptome Profile of Patients With Multiple Sclerosis Treated With Fingolimod: Setting Up a Model for Prediction of Response in a 2-Year Translational Study

BACKGROUND: Fingolimod is a functional sphingosine-1-phosphate antagonist approved for the treatment of multiple sclerosis (MS). Fingolimod affects lymphocyte subpopulations and regulates gene expression in the lymphocyte transcriptome. Translational studies are necessary to identify cellular and mo...

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Detalles Bibliográficos
Autores principales: Moreno-Torres, Irene, González-García, Coral, Marconi, Marco, García-Grande, Aranzazu, Rodríguez-Esparragoza, Luis, Elvira, Víctor, Ramil, Elvira, Campos-Ruíz, Lucía, García-Hernández, Ruth, Al-Shahrour, Fátima, Fustero-Torre, Coral, Sánchez-Sanz, Alicia, García-Merino, Antonio, Sánchez López, Antonio José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068231/
https://www.ncbi.nlm.nih.gov/pubmed/30090102
http://dx.doi.org/10.3389/fimmu.2018.01693

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