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Advances in the Development of Shape Similarity Methods and Their Application in Drug Discovery

Molecular similarity is a key concept in drug discovery. It is based on the assumption that structurally similar molecules frequently have similar properties. Assessment of similarity between small molecules has been highly effective in the discovery and development of various drugs. Especially, two...

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Detalles Bibliográficos
Autores principales:	Kumar, Ashutosh, Zhang, Kam Y. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068280/ https://www.ncbi.nlm.nih.gov/pubmed/30090808 http://dx.doi.org/10.3389/fchem.2018.00315

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