Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset()

OBJECTIVES: To investigate if glucose levels influence seizure patterns. MATERIALS AND METHODS: In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose. RESULTS: Left focal seizure (LFS, n...

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Detalles Bibliográficos
Autores principales: Kinnear, Katie M., Warner, Nicole M., Haltiner, Alan M., Doherty, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068315/
https://www.ncbi.nlm.nih.gov/pubmed/30073145
http://dx.doi.org/10.1016/j.ebcr.2018.03.001
Descripción
Sumario:OBJECTIVES: To investigate if glucose levels influence seizure patterns. MATERIALS AND METHODS: In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose. RESULTS: Left focal seizure (LFS, n = 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2). CONCLUSION: Seizure onset laterality and spread vary with glucose and time of seizure.

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