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Key Residues for the Formation of Aβ42 Amyloid Fibrils
[Image: see text] Formation of amyloid fibrils by Aβ42 protein is a pathological hallmark of Alzheimer’s disease. Aβ42 fibrillization is a nucleation-dependent polymerization process, in which nucleation is the rate-limiting step. Structural knowledge of the fibril nucleus is important to understand...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068601/ https://www.ncbi.nlm.nih.gov/pubmed/30087945 http://dx.doi.org/10.1021/acsomega.8b00887 |