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Combinatorial Approaches to Viral Attenuation

Attenuated viruses have numerous applications, in particular in the context of live viral vaccines. However, purposefully designing attenuated viruses remains challenging, in particular if the attenuation is meant to be resistant to rapid evolutionary recovery. Here we develop and analyze a new atte...

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Detalles Bibliográficos
Autores principales:	Paff, Matthew L., Jack, Benjamin R., Smith, Bartram L., Bull, James J., Wilke, Claus O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068830/ https://www.ncbi.nlm.nih.gov/pubmed/30073203 http://dx.doi.org/10.1128/mSystems.00046-18

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