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Nonlinear Flow Sensor Calibration with an Accurate Syringe

Flow sensors are required for monitoring patients on mechanical ventilation and in respiratory research. Proper calibration is important for ensuring accuracy and can be done with a precision syringe. This procedure, however, becomes complex for nonlinear flow sensors, which are commonly used. The o...

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Autores principales: Biselli, Paolo Jose Cesare, Nóbrega, Raquel Siqueira, Soriano, Francisco Garcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068951/
https://www.ncbi.nlm.nih.gov/pubmed/29976851
http://dx.doi.org/10.3390/s18072163
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author Biselli, Paolo Jose Cesare
Nóbrega, Raquel Siqueira
Soriano, Francisco Garcia
author_facet Biselli, Paolo Jose Cesare
Nóbrega, Raquel Siqueira
Soriano, Francisco Garcia
author_sort Biselli, Paolo Jose Cesare
collection PubMed
description Flow sensors are required for monitoring patients on mechanical ventilation and in respiratory research. Proper calibration is important for ensuring accuracy and can be done with a precision syringe. This procedure, however, becomes complex for nonlinear flow sensors, which are commonly used. The objective of the present work was to develop an algorithm to allow the calibration of nonlinear flow sensors using an accurate syringe. We first noticed that a power law equation could properly fit the pressure-flow relationship of nonlinear flow sensors. We then developed a software code to estimate the parameters for this equation using a 3 L syringe (calibration syringe). Finally, we tested the performance of a calibrated flow sensor using a different 3 L syringe (testing syringe) and a commercially available spirometer. After calibration, the sensor had a bias ranging from −1.7% to 3.0% and precision from 0.012 L to 0.039 L for volumes measured with the 3 L testing syringe. Calibrated sensor performance was at least as good as the commercial sensor. This calibration procedure can be done at the bedside for both clinical and research purposes, therefore improving the accuracy of nonlinear flow sensors.
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spelling pubmed-60689512018-08-07 Nonlinear Flow Sensor Calibration with an Accurate Syringe Biselli, Paolo Jose Cesare Nóbrega, Raquel Siqueira Soriano, Francisco Garcia Sensors (Basel) Article Flow sensors are required for monitoring patients on mechanical ventilation and in respiratory research. Proper calibration is important for ensuring accuracy and can be done with a precision syringe. This procedure, however, becomes complex for nonlinear flow sensors, which are commonly used. The objective of the present work was to develop an algorithm to allow the calibration of nonlinear flow sensors using an accurate syringe. We first noticed that a power law equation could properly fit the pressure-flow relationship of nonlinear flow sensors. We then developed a software code to estimate the parameters for this equation using a 3 L syringe (calibration syringe). Finally, we tested the performance of a calibrated flow sensor using a different 3 L syringe (testing syringe) and a commercially available spirometer. After calibration, the sensor had a bias ranging from −1.7% to 3.0% and precision from 0.012 L to 0.039 L for volumes measured with the 3 L testing syringe. Calibrated sensor performance was at least as good as the commercial sensor. This calibration procedure can be done at the bedside for both clinical and research purposes, therefore improving the accuracy of nonlinear flow sensors. MDPI 2018-07-05 /pmc/articles/PMC6068951/ /pubmed/29976851 http://dx.doi.org/10.3390/s18072163 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Biselli, Paolo Jose Cesare
Nóbrega, Raquel Siqueira
Soriano, Francisco Garcia
Nonlinear Flow Sensor Calibration with an Accurate Syringe
title Nonlinear Flow Sensor Calibration with an Accurate Syringe
title_full Nonlinear Flow Sensor Calibration with an Accurate Syringe
title_fullStr Nonlinear Flow Sensor Calibration with an Accurate Syringe
title_full_unstemmed Nonlinear Flow Sensor Calibration with an Accurate Syringe
title_short Nonlinear Flow Sensor Calibration with an Accurate Syringe
title_sort nonlinear flow sensor calibration with an accurate syringe
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068951/
https://www.ncbi.nlm.nih.gov/pubmed/29976851
http://dx.doi.org/10.3390/s18072163
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