Cargando…

Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing

In this paper, we report on the effect of carboxyl- and amine terminations on a boron-doped diamond surface (BDD) in relation to pH sensitivity. Carboxyl termination was achieved by anodization oxidation in Carmody buffer solution (pH 7). The carboxyl-terminated diamond surface was exposed to nitrog...

Descripción completa

Detalles Bibliográficos
Autores principales: Falina, Shaili, Kawai, Sora, Oi, Nobutaka, Yamano, Hayate, Kageura, Taisuke, Suaebah, Evi, Inaba, Masafumi, Shintani, Yukihiro, Syamsul, Mohd, Kawarada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069108/
https://www.ncbi.nlm.nih.gov/pubmed/29986461
http://dx.doi.org/10.3390/s18072178
_version_ 1783343424382959616
author Falina, Shaili
Kawai, Sora
Oi, Nobutaka
Yamano, Hayate
Kageura, Taisuke
Suaebah, Evi
Inaba, Masafumi
Shintani, Yukihiro
Syamsul, Mohd
Kawarada, Hiroshi
author_facet Falina, Shaili
Kawai, Sora
Oi, Nobutaka
Yamano, Hayate
Kageura, Taisuke
Suaebah, Evi
Inaba, Masafumi
Shintani, Yukihiro
Syamsul, Mohd
Kawarada, Hiroshi
author_sort Falina, Shaili
collection PubMed
description In this paper, we report on the effect of carboxyl- and amine terminations on a boron-doped diamond surface (BDD) in relation to pH sensitivity. Carboxyl termination was achieved by anodization oxidation in Carmody buffer solution (pH 7). The carboxyl-terminated diamond surface was exposed to nitrogen radicals to generate an amine-terminated surface. The pH sensitivity of the carboxyl- and amine-terminated surfaces was measured from pH 2 to pH 12. The pH sensitivities of the carboxyl-terminated surface at low and high pH are 45 and 3 mV/pH, respectively. The pH sensitivity after amine termination is significantly higher—the pH sensitivities at low and high pH are 65 and 24 mV/pH, respectively. We find that the negatively-charged surface properties of the carboxyl-terminated surface due to ionization of –COOH causes very low pH detection in the high pH region (pH 7–12). In the case of the amine-terminated surface, the surface properties are interchangeable in both acidic and basic solutions; therefore, we observed pH detection at both low and high pH regions. The results presented here may provide molecular-level understanding of surface properties with charged ions in pH solutions. The understanding of these surface terminations on BDD substrate may be useful to design diamond-based biosensors.
format Online
Article
Text
id pubmed-6069108
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-60691082018-08-07 Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing Falina, Shaili Kawai, Sora Oi, Nobutaka Yamano, Hayate Kageura, Taisuke Suaebah, Evi Inaba, Masafumi Shintani, Yukihiro Syamsul, Mohd Kawarada, Hiroshi Sensors (Basel) Article In this paper, we report on the effect of carboxyl- and amine terminations on a boron-doped diamond surface (BDD) in relation to pH sensitivity. Carboxyl termination was achieved by anodization oxidation in Carmody buffer solution (pH 7). The carboxyl-terminated diamond surface was exposed to nitrogen radicals to generate an amine-terminated surface. The pH sensitivity of the carboxyl- and amine-terminated surfaces was measured from pH 2 to pH 12. The pH sensitivities of the carboxyl-terminated surface at low and high pH are 45 and 3 mV/pH, respectively. The pH sensitivity after amine termination is significantly higher—the pH sensitivities at low and high pH are 65 and 24 mV/pH, respectively. We find that the negatively-charged surface properties of the carboxyl-terminated surface due to ionization of –COOH causes very low pH detection in the high pH region (pH 7–12). In the case of the amine-terminated surface, the surface properties are interchangeable in both acidic and basic solutions; therefore, we observed pH detection at both low and high pH regions. The results presented here may provide molecular-level understanding of surface properties with charged ions in pH solutions. The understanding of these surface terminations on BDD substrate may be useful to design diamond-based biosensors. MDPI 2018-07-06 /pmc/articles/PMC6069108/ /pubmed/29986461 http://dx.doi.org/10.3390/s18072178 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Falina, Shaili
Kawai, Sora
Oi, Nobutaka
Yamano, Hayate
Kageura, Taisuke
Suaebah, Evi
Inaba, Masafumi
Shintani, Yukihiro
Syamsul, Mohd
Kawarada, Hiroshi
Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing
title Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing
title_full Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing
title_fullStr Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing
title_full_unstemmed Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing
title_short Role of Carboxyl and Amine Termination on a Boron-Doped Diamond Solution Gate Field Effect Transistor (SGFET) for pH Sensing
title_sort role of carboxyl and amine termination on a boron-doped diamond solution gate field effect transistor (sgfet) for ph sensing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069108/
https://www.ncbi.nlm.nih.gov/pubmed/29986461
http://dx.doi.org/10.3390/s18072178
work_keys_str_mv AT falinashaili roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT kawaisora roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT oinobutaka roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT yamanohayate roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT kageurataisuke roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT suaebahevi roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT inabamasafumi roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT shintaniyukihiro roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT syamsulmohd roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing
AT kawaradahiroshi roleofcarboxylandamineterminationonaborondopeddiamondsolutiongatefieldeffecttransistorsgfetforphsensing