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Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs

Kidney exchange programs, which allow a potential living donor whose kidney is incompatible with his or her intended recipient to donate a kidney to another patient in return for a kidney that is compatible for their intended recipient, usually aims to maximize the number of possible kidney exchange...

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Autores principales: Lee, Hyunwoo, Chung, Seokhyun, Cheong, Taesu, Song, Sang Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069132/
https://www.ncbi.nlm.nih.gov/pubmed/30011934
http://dx.doi.org/10.3390/ijerph15071491
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author Lee, Hyunwoo
Chung, Seokhyun
Cheong, Taesu
Song, Sang Hwa
author_facet Lee, Hyunwoo
Chung, Seokhyun
Cheong, Taesu
Song, Sang Hwa
author_sort Lee, Hyunwoo
collection PubMed
description Kidney exchange programs, which allow a potential living donor whose kidney is incompatible with his or her intended recipient to donate a kidney to another patient in return for a kidney that is compatible for their intended recipient, usually aims to maximize the number of possible kidney exchanges or the total utility of the program. However, the fairness of these exchanges is an issue that has often been ignored. In this paper, as a way to overcome the problems arising in previous studies, we take fairness to be the degree to which individual patient-donor pairs feel satisfied, rather than the extent to which the exchange increases social benefits. A kidney exchange has to occur on the basis of the value of the kidneys themselves because the process is similar to bartering. If the matched kidneys are not of the level expected by the patient-donor pairs involved, the match may break and the kidney exchange transplantation may fail. This study attempts to classify possible scenarios for such failures and incorporate these into a stochastic programming framework. We apply a two-stage stochastic programming method using total utility in the first stage and the sum of the penalties for failure in the second stage when an exceptional event occurs. Computational results are provided to demonstrate the improvement of the proposed model compared to that of previous deterministic models.
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spelling pubmed-60691322018-08-07 Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs Lee, Hyunwoo Chung, Seokhyun Cheong, Taesu Song, Sang Hwa Int J Environ Res Public Health Article Kidney exchange programs, which allow a potential living donor whose kidney is incompatible with his or her intended recipient to donate a kidney to another patient in return for a kidney that is compatible for their intended recipient, usually aims to maximize the number of possible kidney exchanges or the total utility of the program. However, the fairness of these exchanges is an issue that has often been ignored. In this paper, as a way to overcome the problems arising in previous studies, we take fairness to be the degree to which individual patient-donor pairs feel satisfied, rather than the extent to which the exchange increases social benefits. A kidney exchange has to occur on the basis of the value of the kidneys themselves because the process is similar to bartering. If the matched kidneys are not of the level expected by the patient-donor pairs involved, the match may break and the kidney exchange transplantation may fail. This study attempts to classify possible scenarios for such failures and incorporate these into a stochastic programming framework. We apply a two-stage stochastic programming method using total utility in the first stage and the sum of the penalties for failure in the second stage when an exceptional event occurs. Computational results are provided to demonstrate the improvement of the proposed model compared to that of previous deterministic models. MDPI 2018-07-14 2018-07 /pmc/articles/PMC6069132/ /pubmed/30011934 http://dx.doi.org/10.3390/ijerph15071491 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Hyunwoo
Chung, Seokhyun
Cheong, Taesu
Song, Sang Hwa
Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs
title Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs
title_full Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs
title_fullStr Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs
title_full_unstemmed Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs
title_short Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs
title_sort accounting for fairness in a two-stage stochastic programming model for kidney exchange programs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069132/
https://www.ncbi.nlm.nih.gov/pubmed/30011934
http://dx.doi.org/10.3390/ijerph15071491
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