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Screening and Identification of Lassa Virus Entry Inhibitors from an FDA-Approved Drug Library

Lassa virus (LASV) belongs to the Mammarenavirus genus (family Arenaviridae) and causes severe hemorrhagic fever in humans. At present, there are no Food and Drug Administration (FDA)-approved drugs or vaccines specific for LASV. Here, high-throughput screening of an FDA-approved drug library was pe...

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Detalles Bibliográficos
Autores principales: Wang, Peilin, Liu, Yang, Zhang, Guangshun, Wang, Shaobo, Guo, Jiao, Cao, Junyuan, Jia, Xiaoying, Zhang, Leike, Xiao, Gengfu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069169/
https://www.ncbi.nlm.nih.gov/pubmed/29899092
http://dx.doi.org/10.1128/JVI.00954-18