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Persistent Replication of a Chikungunya Virus Replicon in Human Cells Is Associated with Presence of Stable Cytoplasmic Granules Containing Nonstructural Protein 3

Chikungunya virus (CHIKV), a mosquito-borne human pathogen, causes a disabling disease characterized by severe joint pain that can persist for weeks, months, or even years in patients. The nonstructural protein 3 (nsP3) plays essential roles during acute infection, but little is known about the func...

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Detalles Bibliográficos
Autores principales: Remenyi, Roland, Gao, Yanni, Hughes, Ruth E., Curd, Alistair, Zothner, Carsten, Peckham, Michelle, Merits, Andres, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069192/
https://www.ncbi.nlm.nih.gov/pubmed/29875241
http://dx.doi.org/10.1128/JVI.00477-18