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Persistent Replication of a Chikungunya Virus Replicon in Human Cells Is Associated with Presence of Stable Cytoplasmic Granules Containing Nonstructural Protein 3
Chikungunya virus (CHIKV), a mosquito-borne human pathogen, causes a disabling disease characterized by severe joint pain that can persist for weeks, months, or even years in patients. The nonstructural protein 3 (nsP3) plays essential roles during acute infection, but little is known about the func...
Autores principales: | Remenyi, Roland, Gao, Yanni, Hughes, Ruth E., Curd, Alistair, Zothner, Carsten, Peckham, Michelle, Merits, Andres, Harris, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069192/ https://www.ncbi.nlm.nih.gov/pubmed/29875241 http://dx.doi.org/10.1128/JVI.00477-18 |
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