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CD8 T Cell Responses to an Immunodominant Epitope within the Nonstructural Protein NS1 Provide Wide Immunoprotection against Bluetongue Virus in IFNAR(−/−) Mice
The development of vaccines against bluetongue, a prevalent livestock disease, has been focused on surface antigens that induce strong neutralizing antibody responses. Because of their antigenic variability, these vaccines are usually serotype restricted. We now show that a single highly conserved n...
Autores principales: | Marín-López, Alejandro, Calvo-Pinilla, Eva, Barriales, Diego, Lorenzo, Gema, Brun, Alejandro, Anguita, Juan, Ortego, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069212/ https://www.ncbi.nlm.nih.gov/pubmed/29875250 http://dx.doi.org/10.1128/JVI.00938-18 |
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