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Towards improving diagnosis of skin diseases by combining deep neural network and human knowledge
BACKGROUND: The emergence of the deep convolutional neural network (CNN) greatly improves the quality of computer-aided supporting systems. However, due to the challenges of generating reliable and timely results, clinical adoption of computer-aided diagnosis systems is still limited. Recent informa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069289/ https://www.ncbi.nlm.nih.gov/pubmed/30066649 http://dx.doi.org/10.1186/s12911-018-0631-9 |
Sumario: | BACKGROUND: The emergence of the deep convolutional neural network (CNN) greatly improves the quality of computer-aided supporting systems. However, due to the challenges of generating reliable and timely results, clinical adoption of computer-aided diagnosis systems is still limited. Recent informatics research indicates that machine learning algorithms need to be combined with sufficient clinical expertise in order to achieve an optimal result. METHODS: In this research, we used deep learning algorithms to help diagnose four common cutaneous diseases based on dermoscopic images. In order to facilitate decision-making and improve the accuracy of our algorithm, we summarized classification/diagnosis scenarios based on domain expert knowledge and semantically represented them in a hierarchical structure. RESULTS: Our algorithm achieved an accuracy of 87.25 ± 2.24% in our test dataset with 1067 images. The semantic summarization of diagnosis scenarios can help further improve the algorithm to facilitate future computer-aided decision support. CONCLUSIONS: In this paper, we applied deep neural network algorithm to classify dermoscopic images of four common skin diseases and archived promising results. Based on the results, we further summarized the diagnosis/classification scenarios, which reflect the importance of combining the efforts of both human expertise and computer algorithms in dermatologic diagnoses. |
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