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Klotho Inhibits Proliferation and Migration of Angiotensin II-Induced Vascular Smooth Muscle Cells (VSMCs) by Modulating NF-κB p65, Akt, and Extracellular Signal Regulated Kinase (ERK) Signaling Activities

BACKGROUND: It has been proven that phenotype shifting, from the contractile phenotype to the synthetic phenotype, of vascular smooth muscle cells (VSMCs), plays an important role in vascular diseases such as atherosclerosis, restenosis, and hypertension. Recently, accumulating evidence suggests tha...

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Detalles Bibliográficos
Autores principales: Yu, Shasha, Chen, Yintao, Chen, Shuang, Ye, Ning, Li, Yan, Sun, Yingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069467/
https://www.ncbi.nlm.nih.gov/pubmed/30004089
http://dx.doi.org/10.12659/MSM.908038