Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis

BACKGROUND: Recent studies show that exosomes are involved in intercellular communication and that abundant circular RNAs (circRNAs) are present within exosomes. However, whether these exosomal circRNAs contribute to tumor invasion and metastasis remains unclear, as do their associated mechanisms. M...

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Detalles Bibliográficos
Autores principales: Li, Jie, Li, Zhonghu, Jiang, Peng, Peng, Minjie, Zhang, Xi, Chen, Kai, Liu, Hui, Bi, Huaqiang, Liu, Xiangde, Li, Xiaowu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069563/
https://www.ncbi.nlm.nih.gov/pubmed/30064461
http://dx.doi.org/10.1186/s13046-018-0822-3

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