Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings

The patients often present to palliative care with intractable nausea and vomiting. This may reduce the effectiveness of oral drugs and significantly affects the quality of life of these patients. Despite multiple drugs available for treatment, it is often difficult to control the symptoms. Olanzapi...

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Autores principales: Gupta, Nishkarsh, Puri, Sidharth, Kumar, Vinod, Garg, Rakesh, Bharati, Sachidanand Jee, Mishra, Seema, Bhatnagar, Sushma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069629/
https://www.ncbi.nlm.nih.gov/pubmed/30111956
http://dx.doi.org/10.4103/IJPC.IJPC_30_18
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author Gupta, Nishkarsh
Puri, Sidharth
Kumar, Vinod
Garg, Rakesh
Bharati, Sachidanand Jee
Mishra, Seema
Bhatnagar, Sushma
author_facet Gupta, Nishkarsh
Puri, Sidharth
Kumar, Vinod
Garg, Rakesh
Bharati, Sachidanand Jee
Mishra, Seema
Bhatnagar, Sushma
author_sort Gupta, Nishkarsh
collection PubMed
description The patients often present to palliative care with intractable nausea and vomiting. This may reduce the effectiveness of oral drugs and significantly affects the quality of life of these patients. Despite multiple drugs available for treatment, it is often difficult to control the symptoms. Olanzapine is an atypical antipsychotic and acts on multiple receptors and may help in treating vomiting in a patient with advanced malignancy. We report a case of gallbladder carcinoma who presented to us with intractable vomiting which was not relieved with a combination of traditional antiemetics but showed marked improvement with olanzapine.
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spelling pubmed-60696292018-08-15 Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings Gupta, Nishkarsh Puri, Sidharth Kumar, Vinod Garg, Rakesh Bharati, Sachidanand Jee Mishra, Seema Bhatnagar, Sushma Indian J Palliat Care Case Report The patients often present to palliative care with intractable nausea and vomiting. This may reduce the effectiveness of oral drugs and significantly affects the quality of life of these patients. Despite multiple drugs available for treatment, it is often difficult to control the symptoms. Olanzapine is an atypical antipsychotic and acts on multiple receptors and may help in treating vomiting in a patient with advanced malignancy. We report a case of gallbladder carcinoma who presented to us with intractable vomiting which was not relieved with a combination of traditional antiemetics but showed marked improvement with olanzapine. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6069629/ /pubmed/30111956 http://dx.doi.org/10.4103/IJPC.IJPC_30_18 Text en Copyright: © 2018 Indian Journal of Palliative Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gupta, Nishkarsh
Puri, Sidharth
Kumar, Vinod
Garg, Rakesh
Bharati, Sachidanand Jee
Mishra, Seema
Bhatnagar, Sushma
Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings
title Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings
title_full Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings
title_fullStr Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings
title_full_unstemmed Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings
title_short Olanzapine in the Treatment of Refractory Nausea and Vomiting in Palliative Care Settings
title_sort olanzapine in the treatment of refractory nausea and vomiting in palliative care settings
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069629/
https://www.ncbi.nlm.nih.gov/pubmed/30111956
http://dx.doi.org/10.4103/IJPC.IJPC_30_18
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