Cargando…

Musculoskeletal manifestations of tuberculosis: An observational study

BACKGROUND: Data of musculoskeletal manifestations of tuberculosis (TB) are limited to case reports, series, or retrospective studies. Therefore, we conducted this study to create awareness among doctors about musculoskeletal manifestations of TB. MATERIALS AND METHODS: This was a prospective observ...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, Nikhil, Bhatnagar, Anuj K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069666/
https://www.ncbi.nlm.nih.gov/pubmed/30112304
http://dx.doi.org/10.4103/jfmpc.jfmpc_7_17
_version_ 1783343542085615616
author Gupta, Nikhil
Bhatnagar, Anuj K
author_facet Gupta, Nikhil
Bhatnagar, Anuj K
author_sort Gupta, Nikhil
collection PubMed
description BACKGROUND: Data of musculoskeletal manifestations of tuberculosis (TB) are limited to case reports, series, or retrospective studies. Therefore, we conducted this study to create awareness among doctors about musculoskeletal manifestations of TB. MATERIALS AND METHODS: This was a prospective observational study conducted at a referral TB Hospital in North India in September and October 2016. The aim of our study was to study musculoskeletal manifestations of TB. We included patients who had active TB as per the World Health Organization 2010 criteria. Patients with other chronic illnesses were excluded. A detailed history, examination, and appropriate investigations (blood, urine, serological, and radiological) of the 100 consecutive patients fulfilling the inclusion criteria were recorded. RESULTS: The mean age of patients was 32.16 ± 12.93 years. Male-to-female ratio was 43:57. The mean duration of disease was 6.85 ± 8.83 months. Of the 100 patients, 60 (60%) had pulmonary TB. The mean duration of antitubercular therapy was 1.79 ± 1.34 months. Fibromyalgia was classified in 21 (21%) patients, polyarthralgia was seen in 9 (9%), Pott's spine in 7 (7%), osteomyelitis in 4 (4%), and scleritis in 2 (2%) patients. Uveitis, tenosynovitis, erythema induratum, subcutaneous abscess, and dactylitis were seen in 1 (1%) patient each. In 21 patients who had fibromyalgia, 11 developed fibromyalgia with the second episode of TB amounting to 60.75% patients. CONCLUSION: This is the first prospective study to look at the musculoskeletal manifestations of TB. Patients with active TB were found to have various rheumatological manifestations.
format Online
Article
Text
id pubmed-6069666
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-60696662018-08-15 Musculoskeletal manifestations of tuberculosis: An observational study Gupta, Nikhil Bhatnagar, Anuj K J Family Med Prim Care Original Article BACKGROUND: Data of musculoskeletal manifestations of tuberculosis (TB) are limited to case reports, series, or retrospective studies. Therefore, we conducted this study to create awareness among doctors about musculoskeletal manifestations of TB. MATERIALS AND METHODS: This was a prospective observational study conducted at a referral TB Hospital in North India in September and October 2016. The aim of our study was to study musculoskeletal manifestations of TB. We included patients who had active TB as per the World Health Organization 2010 criteria. Patients with other chronic illnesses were excluded. A detailed history, examination, and appropriate investigations (blood, urine, serological, and radiological) of the 100 consecutive patients fulfilling the inclusion criteria were recorded. RESULTS: The mean age of patients was 32.16 ± 12.93 years. Male-to-female ratio was 43:57. The mean duration of disease was 6.85 ± 8.83 months. Of the 100 patients, 60 (60%) had pulmonary TB. The mean duration of antitubercular therapy was 1.79 ± 1.34 months. Fibromyalgia was classified in 21 (21%) patients, polyarthralgia was seen in 9 (9%), Pott's spine in 7 (7%), osteomyelitis in 4 (4%), and scleritis in 2 (2%) patients. Uveitis, tenosynovitis, erythema induratum, subcutaneous abscess, and dactylitis were seen in 1 (1%) patient each. In 21 patients who had fibromyalgia, 11 developed fibromyalgia with the second episode of TB amounting to 60.75% patients. CONCLUSION: This is the first prospective study to look at the musculoskeletal manifestations of TB. Patients with active TB were found to have various rheumatological manifestations. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6069666/ /pubmed/30112304 http://dx.doi.org/10.4103/jfmpc.jfmpc_7_17 Text en Copyright: © 2018 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Gupta, Nikhil
Bhatnagar, Anuj K
Musculoskeletal manifestations of tuberculosis: An observational study
title Musculoskeletal manifestations of tuberculosis: An observational study
title_full Musculoskeletal manifestations of tuberculosis: An observational study
title_fullStr Musculoskeletal manifestations of tuberculosis: An observational study
title_full_unstemmed Musculoskeletal manifestations of tuberculosis: An observational study
title_short Musculoskeletal manifestations of tuberculosis: An observational study
title_sort musculoskeletal manifestations of tuberculosis: an observational study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069666/
https://www.ncbi.nlm.nih.gov/pubmed/30112304
http://dx.doi.org/10.4103/jfmpc.jfmpc_7_17
work_keys_str_mv AT guptanikhil musculoskeletalmanifestationsoftuberculosisanobservationalstudy
AT bhatnagaranujk musculoskeletalmanifestationsoftuberculosisanobservationalstudy