Recent advances in the management of malignant pheochromocytoma and paraganglioma: focus on tyrosine kinase and hypoxia-inducible factor inhibitors

Inactivating mutations of the succinate dehydrogenase subunit B ( SDHB) gene and the subsequent stabilization and activation of the hypoxia-inducible factor 2-alpha (HIF2α) unit are recognized hallmarks associated with the development of metastatic pheochromocytomas and paragangliomas (MPPG). Despit...

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Detalles Bibliográficos
Autores principales: Toledo, Rodrigo, Jimenez, Camilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069727/
https://www.ncbi.nlm.nih.gov/pubmed/30109021
http://dx.doi.org/10.12688/f1000research.13995.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069727/
https://www.ncbi.nlm.nih.gov/pubmed/30109021
http://dx.doi.org/10.12688/f1000research.13995.1

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