Cargando…

Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44+ cancer stem cells to 5 azacytidine in hepatocellular carcinoma

BACKGROUND: In hepatocellular carcinoma (HCC), CD133+/CD44+ cells are one subgroup with high stemness and responsible for metastatic relapse and resistance to treatment. Our previous studies have demonstrated that osteopontin (OPN) plays critical roles in HCC metastasis. We further investigated the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Xiaomei, Sheng, Yuanyuan, Yang, Jing, Wang, Chaoqun, Zhang, Rui, Zhu, Ying, Zhang, Ze, Zhang, Kaili, Yan, Shican, Sun, Haoting, Wei, Jinwang, Wang, Xuan, Yu, Xinxin, Zhang, Yu, Luo, Qin, Zheng, Yan, Qiao, Peng, Zhao, Yue, Dong, Qiongzhu, Qin, Lunxiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069805/ https://www.ncbi.nlm.nih.gov/pubmed/30064482 http://dx.doi.org/10.1186/s13046-018-0832-1

Ejemplares similares

Correction: Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44 + cancer stem cells to 5 azacytidine in hepatocellular carcinoma
por: Gao, Xiaomei, et al.
Publicado: (2023)

Exosomal S100A4 derived from highly metastatic hepatocellular carcinoma cells promotes metastasis by activating STAT3
por: Sun, Haoting, et al.
Publicado: (2021)

Osteopontin promotes epithelial-mesenchymal transition of hepatocellular carcinoma through regulating vimentin
por: Dong, Qiongzhu, et al.
Publicado: (2016)

Genome-Wide Association Study Identifies a Genetic Prediction Model for Postoperative Survival in Patients with Hepatocellular Carcinoma
por: Wei, Jinwang, et al.
Publicado: (2019)

Osteopontin and the C-terminal peptide of thrombospondin-4 compete for CD44 binding and have opposite effects on CD133+ cell colony formation
por: Sadvakassova, Gulzhakhan, et al.
Publicado: (2009)

Expression and localisation of osteopontin and prominin-1 (CD133) in patients with endometriosis
por: D’AMICO, FABIO, et al.
Publicado: (2013)

Structural Constraint of Osteopontin Facilitates Efficient Binding to CD44
por: Fnu, Gulimirerouzi, et al.
Publicado: (2021)

The Potential Role of CD44 and CD133 in Colorectal Stem Cell Cancer
por: Abdou Hassan, Wael, et al.
Publicado: (2022)

Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells
por: Desai, Bhavik, et al.
Publicado: (2007)

Cancer Stem Cell Markers CD44, CD133 in Primary Gastric Adenocarcinoma
por: Nosrati, Anahita, et al.
Publicado: (2014)

Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer
por: WANG, CHUNXIA, et al.
Publicado: (2012)

Role of CD44(high)/CD133(high) HCT-116 cells in the tumorigenesis of colon cancer
por: Zhou, Jin-Yong, et al.
Publicado: (2016)

Prognostic value of CD133(+) CD54(+) CD44(+) circulating tumor cells in colorectal cancer with liver metastasis
por: Fang, Chao, et al.
Publicado: (2017)

The dual blockade of MET and VEGFR2 signaling demonstrates pronounced inhibition on tumor growth and metastasis of hepatocellular carcinoma
por: Zhang, Yu, et al.
Publicado: (2018)

Differential regulation of osteopontin and CD44 correlates with infertility status in PCOS patients
por: Paravati, R., et al.
Publicado: (2020)

Coexpression analysis of CD133 and CD44 identifies Proneural and Mesenchymal subtypes of glioblastoma multiforme
por: Brown, Daniel V., et al.
Publicado: (2015)

Clinicopathological significance of CD133 and CD44 expression in infiltrating ductal carcinoma and their relationship to angiogenesis
por: Han, Zhengquan, et al.
Publicado: (2015)

CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure
por: Tsunekuni, Kenta, et al.
Publicado: (2019)

Cobalt ferrite nanoparticle for the elimination of CD133+CD44(+) and CD44(+)CD24(−), in breast and skin cancer stem cells, using non-ionizing treatments
por: Khalili Najafabad, Bahareh, et al.
Publicado: (2023)

Dual-targeting nanomicelles with CD133 and CD44 aptamers for enhanced delivery of gefitinib to two populations of lung cancer-initiating cells
por: Huang, Xiaolong, et al.
Publicado: (2020)

CD133(+)CD54(+)CD44(+) circulating tumor cells as a biomarker of treatment selection and liver metastasis in patients with colorectal cancer
por: Fang, Chao, et al.
Publicado: (2016)

Gliomasphere marker combinatorics: multidimensional flow cytometry detects CD44+/CD133+/ITGA6+/CD36+ signature
por: Erhart, Friedrich, et al.
Publicado: (2018)

CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?
por: Jia, Qingan, et al.
Publicado: (2015)

Single-cell sequencing reveals CD133(+)CD44(−)-originating evolution and novel stemness related variants in human colorectal cancer
por: Zhang, Xiaoyan, et al.
Publicado: (2022)

Expression of the Cancer Stem Cell Markers CD44 and CD133 in Colorectal Cancer: An Immunohistochemical Staining Analysis
por: Hong, Injae, et al.
Publicado: (2015)

Expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocacinoma
por: Yu, Ji-wei, et al.
Publicado: (2010)

Brca1 breast tumors contain distinct CD44(+)/CD24(- )and CD133(+ )cells with cancer stem cell characteristics
por: Wright, Mollie H, et al.
Publicado: (2008)

Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells
por: Friel, Anne M, et al.
Publicado: (2010)

Gottron’s papules exhibit dermal accumulation of CD44 variant 7 (CD44v7) and its binding partner osteopontin: a unique molecular signature
por: Kim, Jessica S., et al.
Publicado: (2012)

Immunohistochemical Detection of Cancer Stem Cell Related Markers CD44 and CD133 in Metastatic Colorectal Cancer Patients
por: Pitule, Pavel, et al.
Publicado: (2014)

Effects of flavopiridol on critical regulation pathways of CD133(high)/CD44(high) lung cancer stem cells
por: Bozok Cetintas, Vildan, et al.
Publicado: (2016)

The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication
por: Shirasaki, Takayoshi, et al.
Publicado: (2018)

Osteopontin inhibits osteoarthritis progression via the OPN/CD44/PI3K signal axis
por: Liu, Qing, et al.
Publicado: (2020)

Expression and Clinical Significance of Cancer Stem Cell Markers CD24, CD44, and CD133 in Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis
por: Durko, L., et al.
Publicado: (2017)

Insulin-like growth factor 1-induced enolase 2 deacetylation by HDAC3 promotes metastasis of pancreatic cancer
por: Zheng, Yan, et al.
Publicado: (2020)

Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma
por: Hou, Ya-Chin, et al.
Publicado: (2014)

Oxytetracycline have the therapeutic efficiency in CD133(+) HCC population through suppression CD133 expression by decreasing of protein stability of CD133
por: Song, Yeonhwa, et al.
Publicado: (2018)

CD44 activation state regulated by the CD44v10 isoform determines breast cancer proliferation
por: Guo, Qian, et al.
Publicado: (2021)

Induced growth inhibition, cell cycle arrest and apoptosis in CD133(+)/CD44(+) prostate cancer stem cells by flavopiridol
por: SONER, BURAK CEM, et al.
Publicado: (2014)

Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity
por: Brown, Daniel V., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_r91alr2dl528sssl5mru4voa4f