Cargando…
Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC
BACKGROUND: The death receptors TRAIL-R1 and TRAIL-R2 are frequently overexpressed in cancer and there is an emerging evidence for their important role in malignant progression, also in the case of pancreatic ductal adenocarcinoma (PDAC). In their canonical localization at the plasma membrane, TRAIL...
Autores principales: | Gundlach, Jan-Paul, Hauser, Charlotte, Schlegel, Franka Maria, Böger, Christine, Röder, Christian, Röcken, Christoph, Becker, Thomas, Egberts, Jan-Hendrik, Kalthoff, Holger, Trauzold, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069838/ https://www.ncbi.nlm.nih.gov/pubmed/30064384 http://dx.doi.org/10.1186/s12885-018-4688-8 |
Ejemplares similares
-
Prognostic significance of high mobility group A2 (HMGA2) in pancreatic ductal adenocarcinoma: malignant functions of cytoplasmic HMGA2 expression
por: Gundlach, Jan-Paul, et al.
Publicado: (2021) -
The novel TRAIL-receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells
por: Legler, Karen, et al.
Publicado: (2018) -
CD95L Inhibition Impacts Gemcitabine-Mediated Effects and Non-Apoptotic Signaling of TNF-α and TRAIL in Pancreatic Tumor Cells
por: Rashid, Khalid, et al.
Publicado: (2021) -
Compartmentalization of TNF-related apoptosis-inducing ligand (TRAIL) death receptor functions: emerging role of nuclear TRAIL-R2
por: Bertsch, U, et al.
Publicado: (2014) -
The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection
por: Miarka, Lauritz, et al.
Publicado: (2019)