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Combination of Chymostatin and Aliskiren attenuates ER stress induced by lipid overload in kidney tubular cells
BACKGROUND: Lipotoxicity plays an important role in the pathogenesis of kidney injury. Our previous study demonstrated that activation of local renin-angiotensin system (RAS) was involved in saturated free fatty acids palmitic acid (PA)-induced tubular cell injuries. The current study aims to invest...
Autores principales: | Qiu, Miaojuan, Li, Suchun, Jin, Lizi, Feng, Pinning, Kong, Yonglun, Zhao, Xiaoduo, Lin, Yu, Xu, Yunyun, Li, Chunling, Wang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069859/ https://www.ncbi.nlm.nih.gov/pubmed/30064425 http://dx.doi.org/10.1186/s12944-018-0818-1 |
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